Localization of breakpoints by polymerase chain reactions in Burkitt's lymphoma with 8;14 translocations
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چکیده
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Localization of breakpoints by polymerase chain reactions in Burkitt's lymphoma with 8;14 translocations.
Translocations involving chromosomes 8 and 14 in Burkitt's lymphoma (BL) often involve the switch mu (Smu) region on chromosome 14, which contains multiple repeats. This has enabled us to use the polymerase chain reaction (PCR) to detect breakpoints that involve this region on chromosome 14 and the c-myc gene on chromosome 8. Using pairs of flanking primers, each pair including one annealing to...
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ژورنال
عنوان ژورنال: Blood
سال: 1990
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v75.9.1848.bloodjournal7591848